Impact of ENDS on oxidative stress: a Replica project review

An independent review by the Replica project team examines the impact of tobacco smoke and electronic nicotine delivery systems use on oxidative stress, the precursor of the so-called tobacco related diseases (respiratory and cardiovascular diseases, tumors). To date, the scientific evidence available constitutes a puzzle of information, which, despite experimental and procedural limitations of international studies , already shows a reduced impact of ENDS on oxidative stress compared to cigarette smoking, even if some research have concluded that they do not completely eliminate it, leaving the question still pending 

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