Two CoEHAR researchers will be part of this great event: The CoEHAR Director, Giovanni Li Volti, who is also PI of the replica project, will discuss the latest results of the Replica project and the IN silicon Science Pi, Dr. Renée O’Leary, will present her latest work.
On behalf of CoEHAR, the Center of Excellence for the acceleration of Harm Reduction, Dr. Lia Emma, researcher of the Replica project, will attend the conference to present the abstract "Cytotoxicity evaluation of vanillin in electronic cigarette liquids on human aortic artery endothelial cells”.
The third phase of the Replica project is in the prime of its activity: CoEHAR researchers successfully replicated the study published by Rudd and colleagues in 2020 and the data obtained not only show slight or no cytotoxic, mutagenic and genotoxic effects induced by the e-cigarette aerosol, but the work by researchers of Catania covered some methodological gaps and limitations in the original work.
An independent review by the Replica project team examines the impact of tobacco smoke and electronic nicotine delivery systems use on oxidative stress, the precursor of the so-called tobacco related diseases (respiratory and cardiovascular diseases, tumors). To date, the scientific evidence available constitutes a puzzle of information, which, despite experimental and procedural limitations of international studies , already shows a reduced impact of ENDS on oxidative stress compared to cigarette smoking, even if some research have concluded that they do not completely eliminate it, leaving the question still pending
The Replica project team activity and the results of the studies on the reduced cytotoxicity and inflammation induced by cigarette smoke and ENDS aerosol will be presented during the XVI edition of the Congress of the Italian Federation of Life Sciences (FISV), which represents over 10.0000 Italian scientists and which will take place from 14 to 16 September 2022 in Naples
CoEHAR researchers, involved in the Replica project, have shown that switching to electronic cigarettes and heated tobacco products reduce the vascular damage and the onset of diseases such as arteriosclerosis.
According to Giovanni Li Volti, director of CoEHAR, the Center of Excellence for the Acceleration of Harm Reduction in Catania, "To date, the results that have emerged confirm that there are no longer any doubts: electronic cigarettes are more than 95% less harmful than conventional cigarettes”
From November 25thto 28ththe Coehar will host the international partners of the Replica project, the third of the 9 projects presented last June at the COEHAR