CoEHAR welcomes the International partners of Replica

“We would like to thank all the partners for accepting to continue this important partnership with the new edition of the Replica Project” stated Prof. Giovanni Li Volti, recently reconfirmed COEHAR Director “The goal for this new session of experiments is to replicate published scientific works dealing with the impact of cigarette smoke and RRP on the progression of cancer and in particular to molecular mechanisms of chemoresistance. In particular, the result of such studies will make also the difference in terms of harm reduction strategies for a particular vulnerable population of patients and improve the quality of their life in terms of life expectancy and adverse reactions to chemotherapy”

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MAGNIFICAT: published the innovative protocol on dual users and harm reduction potential

The MAGNIFICAT study, strongly advocated by Prof. Riccardo Polosa, will evaluate the effects of the combined use of conventional cigarettes and electronic cigarettes on human health, quantifying this impact by collecting samples, researching and describing the core of different levels of dual use on exposure to toxic substances and harm reduction, and using specific biomarkers, clinical endpoints, and behavioral correlations

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HOW TO REDUCE THE HARM CAUSED BY CIGARETTE SMOKE ON ORAL HEALTH AND TEETH?

The data from these works as a whole can be used to assess the impact in terms of risk/benefit ratio of the regular use of combustion-free products, assisting the efforts of public health authorities in encouraging smokers to quit, especially those who perceive their smoke-damaged smile as a barrier to personal health or work and social relationships.

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Groundbreaking Global Initiative to Investigate Oral Health Impacts of Combustion-Free Nicotine Delivery Alternatives: the SMILE Study

The study has been designed with the help of experts from Germany, UK, Italy, Poland, Moldova, and Indonesia. SMILE study is being conducted in four dental clinics across four different countries (Italy, Poland, Moldova, and Indonesia). Volunteer enrollment was completed in August 2023 and results will be expected to be available in 2025.

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CoEHAR research reveals whiter teeth in former smokers using E-Cigarettes or Heated Tobacco Products than tobacco smokers 

The study marks the first of its kind, shedding light on a novel aspect of oral health among users of combustion-free nicotine products. These findings underscore the aesthetic benefits associated with ECs and HTPs use, signifying a significant departure from the well-known dental color implications of tobacco smoking. As patients increasingly prioritize aesthetics, evident in the growing prevalence of purely cosmetic dental procedures, and with smoking being a prevalent factor, this result serves as a compelling incentive to quit smoking.

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